Browse student projects below. You can get in touch with any student by clicking the arrow in a profile and filling out the form.
Surviving the rigours of the gut, an internal system designed to keep intruders at bay, can prove a challenge. Many probiotic products currently available claim health benefits to the consumer, do these “happy bacteria” actually survive ingestion? An evaluation of survival and growth rates of probiotics with simulated gastric fluids.
This study compares the effectiveness of expensive trade-marked antimicrobial soaps and low-cost ones and if either acts better than ash and water in removing bacteria from the palm. The result suggested that the cheap soap and ash are more effective over the expensive soap in removing bacteria from the palm.
Contact Ugochukwu Angelo
Bioluminescence is the emission of light which is produced by living organisms such as bioluminescent bacteria, these bioluminescent bacteria can be found growing on different species of rotting fish. The proposed research aims to determine which species of bioluminescent bacteria grow on certain species of fish.
Dust contains shed skin cells from humans. These cells contain DNA that can be forensically analysed. The objective of this study is to deduce whether dust samples from specific rooms contain DNA that matches with the occupants’ DNA and if the quantity of DNA in the samples increases over time.
High prevalence rates of breast cancer, treatments such as chemotherapy have many side effects. Curcumin, a home remedy which is used by many over the world and has anti-inflammatory effects with no side effects. My research investigates Curcumin has the potential to be the next treatment for breast cancer.
Crops and food production rely on the populations of honeybees and these populations are at risk due to a range of RNA viruses. This research focuses on the most common RNA viruses found in Apis mellifera; deformed wing virus and Sacbrood virus. Methods used: RNA extraction, reverse transcription and RT-qPCR.
Chronic diseases caused by oxidative stress can be managed by implementing a healthy diet and exercise; though exercise itself creates oxidative stress. Soya isoflavones have antioxidant properties which are proposed to reduce oxidative stress. This study looks at diet supplementation with soya isoflavones to offset oxidative stress in exercising males.
With high prevalency rates of breast cancer and treatments like chemotherapy having many side effects, this research investigates if curcumin has the potential to be the next breast cancer treatment. Curcumin, a home remedy which is used by many over the world, has anti-inflammatory effects with no side effects.
Tackle breast cancer using a flavonoid from honey and plants including passion flowers. A readily available dietary supplement, Chrysin has shown anti-inflammatory and anti-cancerous properties. MTT assays were used to determine inhibitory properties against MCF-7 breast cancer cells against chemotherapy drug doxorubicin and determine if synergetic values with Chrysin exist.
Gastrointestinal cancers are the second most common cause of cancer death in the UK, with a relatively low survival rate. The proposed research looks to identify whether green tea can be effective in cancer treatment, specifically the flavonoid epigallcatechin-3-gallate and its effects on gastrointestinal tract cancer growth.
Indications are that stress is affecting more students than in previous years. This study aims to determine whether students with responsibilities outside of their studies, such as children or jobs, are more stressed than those students with no obligations by measuring levels of a stress hormone in their hair.
Sport is promoted as a means of maintaining a healthy lifestyle, but excessive exercise can have a negative impact on the immune system. This study looks at the impact of different sport participation on cortisol levels which can affect the immune system to see if different sports vary in response.
High cost chemotherapy for colon cancer has led to the search for naturally sourced alternative treatments. This study aimed to investigate the previously untested effect of two cancer-preventing flavonoids, quercetin and apigenin, alone and in combination on the growth of TC-7 cells using an MTT assay.
This study investigated the neuronal and cardioprotective effect of DHA from algal oil, and compared lipid peroxidation in fish oil and algal oil. Algal source of DHA supplements resulted in a significant improvement in memory and reaction time. Fish oil supplement has higher level of lipid peroxidation than algal oil.
Since the 1980s the prevalence of obesity has tripled and continues to rise rapidly. Clinical treatments are available to assist with weight loss, however, these are not always long-term solutions. This research aims to identify whether the anthocyanin, pelargonidin can inhibit adipocyte proliferation on L929 and SGBS cells.
As the prevalence of gastrointestinal disorders increases, the use of over-the-counter medications also increases. This research study aims to investigate the chemical composition, antioxidant, antimicrobial and pH buffering capacity of O. basilicum that may relate to its reported gastrointestinal effects.
Nigella sativa has been used across the world as an antibacterial medicine, though little data to support its efficacy exists. If proven effective, it may be an alternative to antibiotics. This study aims to determine its ability to inhibit the growth of Staphylococcus aureus and it's Methicillin resistant strain (MRSA).
Toothpaste is commonly used to maintain a good standard of oral health with many main brands containing fluoride as the active antimicrobial agent. The proposed research aims to compare fluoride and Aloe Vera’s effect on Streptococcus mutans and Neisseria sicca as a model of the conditions within the oral cavity.
Cancer is a leading cause of morbidity and its incidence is increasing. This sets a precedent for research into an affordable means to treat/prevent cancer. The aims of this study were to find identify whether or not Nigella sativa (a naturally occurring flower) was a suitable treatment for this disease.
With 3.3 million more people purchasing a "free-from" product in 2016 compared to 2015, research into how these alternative products may be affecting our gastrointestinal health is emerging. This study aims to compare the in vitro growth of common small intestinal microbiota, when inoculated into Cow’s milk and dairy-free alternative milk.
Prolonged use of chemotherapy doxorubicin has damaging biochemical and physiological side effects on cancer patients. By conducting colorimetric MTT viability assays on human colon adenocarcinoma cells (Caco-2/TC7), the cytotoxic effect of dietary flavonoid naringenin plus lower doses of doxorubicin is evaluated for treatment by measuring the cell line’s mitochondrial activity.
The use of antiseptic agents in daily life has largely increased in the past few years. This increase has impacted the investigation of how the physiological stress of exercise influences the growth of commensal bacteria, hence the need to determine how effective antiseptic agents are necessary for decreasing skin microbiota.
Saccharin is an artificial sweetener used for more than a century. Alteration of the gut microbiota by Sodium Saccharin may lead to illness. Does saccharin have antimicrobial properties on some of the microbiota in the intestine. Saccharin is widespread in western food to prevent tooth decay and lower calories.
The effects of baicalein found in Scutellaria baicalensis was examined on breast cancer cell growth undergoing chemotherapy treatment and synergistic effect of baicalein with chemotherapy agents. Baicalein will affect breast cancer cells and chemotherapy efficacy due to its anti-inflammatory effects and can therefore aid in reducing tumour cell proliferation.
Citrus fruits may reduce postprandial blood glucose peaks associated with the Western diet. This study aimed to measure the effects of lemon and orange on blood glucose concentration in healthy human subjects. Nutritional assays were also conducted to quantify anti-glycaemic properties and assess their individual effects.
Soya contains isoflavones, genistein and daidzein, known to mimic oestrogen reportedly decreasING myogenesis and could be affecting neuromuscular disease patients. The aim of this project was to identify soya isoflavones’ effect on C2C12 mouse muscle cell viability using a colorimetric MTT assay and measuring gene expression using qRT-PCR.
According to the UK food standards agency approximately 1.3 billion tons of food is wasted every year due to fungal and bacterial spoilage. Therefore, the aim is to investigate the active ingredient in crushed garlic (allicin) and its effect in inhibiting the growth of unknown isolated bacteria from raw ground meat.
Contact Ida Sarfowah
Interest in the human microbiome has rapidly increased in recent years, however specific research of the scalp microbiome is lacking. Investigating the enumeration and diversity of the human scalp microbiome after hair washing to identify whether factors such as age, gender and hair length impact upon the scalp microbiome.
The Western diet is emerging as a negative influence on intestinal microbiota and their role within the digestive system, causing consequences for human health. This study aims to determine whether Western dietary sugars have the potential to cause dysbacteriosis, using Escherichia coli and Enterococcus faecalis as examples.
The study was carried out to make comparisons of the effectiveness of alcohol-based off the shelf trademarked mouthwashes against their non-alcohol based counterpart to the bacteria which occupy the human oral cavity, and also test the effectiveness of salt water as an alternative comparing them to a known antibiotic (penicillin).
The Western diet has shown to cause a number of health problems relating to diseases such as type two diabetes, which is centered around the metabolic syndrome. This study investigates the beneficial glycemic affects of figs to determine if it can reduce risk of type two diabetes.
The Miswak stick was recommended by Prophet Muhammad 1400 years ago to clean teeth before the advent o the modern toothbrush, and the practice continues to this day. But why was Miswak recommended? The proposed research aims to identify the Anti-microbial, Anti-oxidant, Mechanical and Stain removal properties of the Miswak stick.